Drug interactions
Entecavir + Telavancin
Severity: Moderate
Entecavir and Telavancin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Telavancin is nephrotoxic, and entecavir is cleared by the kidneys through filtration and tubular secretion. Reduced renal function from telavancin could raise entecavir exposure.
What this interaction means in plain words
Entecavir and Telavancin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Entecavir belongs to Anti Virals; Telavancin belongs to Anti Bacterial.
Why it happens
Telavancin-induced renal impairment may reduce renal elimination of entecavir.
What to do
Monitor serum creatinine and adjust the entecavir dose to creatinine clearance if renal function declines.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Telavancin
- Telavancin + Thioridazine Contraindicated
- Adagrasib + Telavancin Major
- Amiodarone + Telavancin Major
- Amisulpride + Telavancin Major
- Anagrelide + Telavancin Major
- Arsenic trioxide + Telavancin Major
Other interactions of Entecavir
Frequently asked questions
Can I take Entecavir with Telavancin?
MediHelp rates the interaction as moderate. Entecavir and Telavancin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Telavancin is nephrotoxic, and entecavir is cleared by the kidneys through filtration and tubular secretion. Reduced renal function from telavancin could raise entecavir exposure.
How serious is the interaction between Entecavir and Telavancin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and adjust the entecavir dose to creatinine clearance if renal function declines.
What other medicines interact with Telavancin?
MediHelp also lists interactions of Telavancin with, for example, Thioridazine, Adagrasib, Amiodarone. The full list is on the Telavancin page.
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