Drug interactions
Ephedrine + Formoterol-mometasone
Severity: Moderate
Ephedrine and Formoterol-mometasone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ephedrine is a sympathomimetic and adds to the cardiovascular stimulation of formoterol, which can cause tachycardia, palpitations and raised blood pressure. Both drugs can also lower serum potassium, which adds to arrhythmia risk in susceptible patients.
What this interaction means in plain words
Ephedrine and Formoterol-mometasone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Ephedrine belongs to Cardiovascular; Formoterol-mometasone belongs to Respiratory.
Why it happens
Additive beta-adrenergic and sympathomimetic stimulation, with beta-2 mediated intracellular potassium shift.
What to do
Monitor heart rate, blood pressure and serum potassium, particularly in patients with cardiovascular disease. Reduce or stop ephedrine if tachyarrhythmia or hypertension develops.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Formoterol-mometasone
Other interactions of Ephedrine
- Ephedrine + Isocarboxazid Contraindicated
- Ephedrine + Phenelzine Contraindicated
- Ephedrine + Procarbazine Contraindicated
- Ephedrine + Rasagiline Contraindicated
- Ephedrine + Selegiline Contraindicated
- Ephedrine + Tranylcypromine Contraindicated
Frequently asked questions
Can I take Ephedrine with Formoterol-mometasone?
MediHelp rates the interaction as moderate. Ephedrine and Formoterol-mometasone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ephedrine is a sympathomimetic and adds to the cardiovascular stimulation of formoterol, which can cause tachycardia, palpitations and raised blood pressure. Both drugs can also lower serum potassium, which adds to arrhythmia risk in susceptible patients.
How serious is the interaction between Ephedrine and Formoterol-mometasone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate, blood pressure and serum potassium, particularly in patients with cardiovascular disease. Reduce or stop ephedrine if tachyarrhythmia or hypertension develops.
What other medicines interact with Formoterol-mometasone?
MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.
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