Drug interactions
Eribulin + Goserelin
Severity: Moderate
Eribulin and Goserelin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Eribulin can prolong the QT interval, and androgen deprivation with goserelin may also do so. The combination may raise the risk of torsades de pointes, especially with electrolyte disturbances.
What this interaction means in plain words
Eribulin and Goserelin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Eribulin belongs to Oncology; Goserelin belongs to Endocrine.
Why it happens
Additive QT prolongation from eribulin and testosterone suppression by goserelin.
What to do
Obtain a baseline ECG and monitor it periodically, and correct potassium and magnesium before and during eribulin treatment.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Goserelin
Other interactions of Eribulin
Frequently asked questions
Can I take Eribulin with Goserelin?
MediHelp rates the interaction as moderate. Eribulin and Goserelin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Eribulin can prolong the QT interval, and androgen deprivation with goserelin may also do so. The combination may raise the risk of torsades de pointes, especially with electrolyte disturbances.
How serious is the interaction between Eribulin and Goserelin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain a baseline ECG and monitor it periodically, and correct potassium and magnesium before and during eribulin treatment.
What other medicines interact with Goserelin?
MediHelp also lists interactions of Goserelin with, for example, Amisulpride, Arsenic trioxide, Artemether / lumefantrine. The full list is on the Goserelin page.
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