Drug interactions
Eribulin + Ozanimod
Severity: Moderate
Eribulin and Ozanimod: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Eribulin can prolong the QT interval, and ozanimod can slow heart rate on initiation. Together they may increase the risk of arrhythmia.
What this interaction means in plain words
Eribulin and Ozanimod can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Eribulin belongs to Oncology; Ozanimod belongs to Central Nervous System.
Why it happens
Additive effects on cardiac conduction: QT prolongation from eribulin and bradycardia from ozanimod.
What to do
Obtain a baseline ECG before starting ozanimod and monitor heart rate and ECG in patients on eribulin. Correct electrolyte abnormalities.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Eribulin
Other interactions of Ozanimod
- Isocarboxazid + Ozanimod Contraindicated
- Linezolid + Ozanimod Contraindicated
- Ozanimod + Phenelzine Contraindicated
- Ozanimod + Procarbazine Contraindicated
- Ozanimod + Rasagiline Contraindicated
- Ozanimod + Safinamide Contraindicated
Frequently asked questions
Can I take Eribulin with Ozanimod?
MediHelp rates the interaction as moderate. Eribulin and Ozanimod can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Eribulin can prolong the QT interval, and ozanimod can slow heart rate on initiation. Together they may increase the risk of arrhythmia.
How serious is the interaction between Eribulin and Ozanimod?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain a baseline ECG before starting ozanimod and monitor heart rate and ECG in patients on eribulin. Correct electrolyte abnormalities.
What other medicines interact with Eribulin?
MediHelp also lists interactions of Eribulin with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Eribulin page.
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