Drug interactions
Eribulin + Tiotropium-olodaterol
Severity: Moderate
Eribulin and Tiotropium-olodaterol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Eribulin can prolong the QT interval and olodaterol may contribute to QT effects and hypokalemia. The combination may increase the risk of arrhythmia in susceptible patients.
What this interaction means in plain words
Eribulin and Tiotropium-olodaterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Eribulin belongs to Oncology; Tiotropium-olodaterol belongs to Respiratory.
Why it happens
Possible additive QT prolongation.
What to do
Monitor ECG and correct potassium and magnesium abnormalities. Take particular care in patients with heart failure or bradyarrhythmias.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Tiotropium-olodaterol
Other interactions of Eribulin
Frequently asked questions
Can I take Eribulin with Tiotropium-olodaterol?
MediHelp rates the interaction as moderate. Eribulin and Tiotropium-olodaterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Eribulin can prolong the QT interval and olodaterol may contribute to QT effects and hypokalemia. The combination may increase the risk of arrhythmia in susceptible patients.
How serious is the interaction between Eribulin and Tiotropium-olodaterol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and correct potassium and magnesium abnormalities. Take particular care in patients with heart failure or bradyarrhythmias.
What other medicines interact with Tiotropium-olodaterol?
MediHelp also lists interactions of Tiotropium-olodaterol with, for example, Amisulpride, Arformoterol, Arsenic trioxide. The full list is on the Tiotropium-olodaterol page.
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