Drug interactions
Eslicarbazepine + Rosuvastatin
Severity: Minor
Eslicarbazepine and Rosuvastatin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Eslicarbazepine is a weak CYP3A4 inducer and may modestly lower exposure to some statins. Rosuvastatin is minimally metabolised by CYP3A4, so a meaningful effect is unlikely, although a small reduction in exposure has been described for it.
What this interaction means in plain words
Eslicarbazepine and Rosuvastatin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Eslicarbazepine belongs to Central Nervous System; Rosuvastatin belongs to Cardiovascular.
Why it happens
Weak enzyme and possibly transporter induction by eslicarbazepine may slightly lower rosuvastatin exposure.
What to do
No routine dose change is needed. Check the lipid profile after starting eslicarbazepine and adjust the statin dose if lipid control worsens.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Rosuvastatin
Other interactions of Eslicarbazepine
- Eslicarbazepine + Mavacamten Contraindicated
- Eslicarbazepine + Rilpivirine Contraindicated
- Artemether / lumefantrine + Eslicarbazepine Major
- Avapritinib + Eslicarbazepine Major
- Bedaquiline + Eslicarbazepine Major
- Benzhydrocodone / acetaminophen + Eslicarbazepine Major
Frequently asked questions
Can I take Eslicarbazepine with Rosuvastatin?
MediHelp rates the interaction as minor. Eslicarbazepine and Rosuvastatin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Eslicarbazepine is a weak CYP3A4 inducer and may modestly lower exposure to some statins. Rosuvastatin is minimally metabolised by CYP3A4, so a meaningful effect is unlikely, although a small reduction in exposure has been described for it.
How serious is the interaction between Eslicarbazepine and Rosuvastatin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine dose change is needed. Check the lipid profile after starting eslicarbazepine and adjust the statin dose if lipid control worsens.
What other medicines interact with Rosuvastatin?
MediHelp also lists interactions of Rosuvastatin with, for example, Atazanavir, Cyclosporin, Darolutamide. The full list is on the Rosuvastatin page.
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