Drug interactions
Estrogens esterified + Teriflunomide
Severity: Minor
Estrogens esterified and Teriflunomide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Teriflunomide weakly induces CYP1A2 and may slightly reduce estrogen exposure. The clinical effect is generally small.
What this interaction means in plain words
Estrogens esterified and Teriflunomide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Weak CYP1A2 induction by teriflunomide may increase estrogen metabolism.
What to do
No routine change is needed. Monitor for return of menopausal symptoms or breakthrough bleeding and adjust the estrogen dose if needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Teriflunomide
Frequently asked questions
Can I take Estrogens esterified with Teriflunomide?
MediHelp rates the interaction as minor. Estrogens esterified and Teriflunomide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Teriflunomide weakly induces CYP1A2 and may slightly reduce estrogen exposure. The clinical effect is generally small.
How serious is the interaction between Estrogens esterified and Teriflunomide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed. Monitor for return of menopausal symptoms or breakthrough bleeding and adjust the estrogen dose if needed.
What other medicines interact with Teriflunomide?
MediHelp also lists interactions of Teriflunomide with, for example, Ifosfamide, Lomustine, Amiodarone. The full list is on the Teriflunomide page.
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