Drug reference
teriflunomide
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Central Nervous System (MS Drugs)
Mechanism of action
Immunomodulatory agent that inhibits dihydroorotate dehydrogenase, a mitochondrial enzyme involved in de novo pyrimidine synthesis Exact mechanism of action on multiple sclerosis is unknown; may involve reducing the number of lymphocytes in the CNS
Common side effects
- Alopecia
- Headache
- Nausea
- Paresthesia
- Influenza
- Increased ALT
- Diarrhea
Related conditions
Frequently asked questions
What drug class is teriflunomide?
teriflunomide belongs to: Central Nervous System.
How does teriflunomide work?
Immunomodulatory agent that inhibits dihydroorotate dehydrogenase, a mitochondrial enzyme involved in de novo pyrimidine synthesis Exact mechanism of action on multiple sclerosis is unknown; may involve reducing the number of lymphocytes in the CNS
What are the common side effects of teriflunomide?
Alopecia, Headache, Nausea, Paresthesia, Influenza, Increased ALT, Diarrhea
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