Drug interactions
Ethacrynic acid + Formoterol-mometasone
Severity: Moderate
Ethacrynic acid and Formoterol-mometasone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Formoterol, ethacrynic acid and corticosteroids can each lower serum potassium. Used together they may cause clinically significant hypokalemia, which raises the risk of cardiac arrhythmias, especially with underlying heart disease or digoxin use.
What this interaction means in plain words
Ethacrynic acid and Formoterol-mometasone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Ethacrynic acid belongs to Cardiovascular; Formoterol-mometasone belongs to Respiratory.
Why it happens
Additive hypokalemia from loop diuretic potassium wasting, beta-2 mediated intracellular potassium shift and mineralocorticoid activity of corticosteroids.
What to do
Monitor serum potassium and magnesium periodically, particularly at the start of therapy or with high doses. Replace potassium as needed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Formoterol-mometasone
Other interactions of Ethacrynic acid
Frequently asked questions
Can I take Ethacrynic acid with Formoterol-mometasone?
MediHelp rates the interaction as moderate. Ethacrynic acid and Formoterol-mometasone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Formoterol, ethacrynic acid and corticosteroids can each lower serum potassium. Used together they may cause clinically significant hypokalemia, which raises the risk of cardiac arrhythmias, especially with underlying heart disease or digoxin use.
How serious is the interaction between Ethacrynic acid and Formoterol-mometasone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium and magnesium periodically, particularly at the start of therapy or with high doses. Replace potassium as needed.
What other medicines interact with Formoterol-mometasone?
MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.
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