Drug interactions
Ethacrynic acid + Vitamin b1
Severity: Minor
Ethacrynic acid and Vitamin b1: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Loop diuretics increase urinary thiamine loss, and long-term use may contribute to thiamine deficiency, especially in heart failure patients with poor intake. Ethacrynic acid is expected to share this effect.
What this interaction means in plain words
Ethacrynic acid and Vitamin b1 have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Ethacrynic acid belongs to Cardiovascular; Vitamin b1 belongs to Gastrointestinal Tract.
Why it happens
Diuresis increases renal excretion of water-soluble thiamine.
What to do
Consider assessing thiamine status or supplementing in patients on long-term high-dose loop diuretics with poor nutrition.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Vitamin b1
- Ethanol + Vitamin b1 Major
- Bumetanide + Vitamin b1 Minor
- Furosemide + Vitamin b1 Minor
- Omadacycline + Vitamin b1 Minor
- Patiromer + Vitamin b1 Minor
- Torsemide + Vitamin b1 Minor
Other interactions of Ethacrynic acid
Frequently asked questions
Can I take Ethacrynic acid with Vitamin b1?
MediHelp rates the interaction as minor. Ethacrynic acid and Vitamin b1 have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Loop diuretics increase urinary thiamine loss, and long-term use may contribute to thiamine deficiency, especially in heart failure patients with poor intake. Ethacrynic acid is expected to share this effect.
How serious is the interaction between Ethacrynic acid and Vitamin b1?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Consider assessing thiamine status or supplementing in patients on long-term high-dose loop diuretics with poor nutrition.
What other medicines interact with Vitamin b1?
MediHelp also lists interactions of Vitamin b1 with, for example, Ethanol, Bumetanide, Furosemide. The full list is on the Vitamin b1 page.
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