Drug interactions
Etodolac + Potassium iodide
Severity: Minor
Etodolac and Potassium iodide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Potassium iodide supplies a potassium load, and NSAIDs can reduce renal potassium excretion. Together they may raise serum potassium, particularly in patients with renal impairment or other risk factors for hyperkalemia.
What this interaction means in plain words
Etodolac and Potassium iodide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Etodolac belongs to Musculoskeletal; Potassium iodide belongs to Endocrine.
Why it happens
NSAID-induced suppression of renal prostaglandins and renin-aldosterone activity reduces potassium excretion, adding to the potassium load from the salt.
What to do
Check serum potassium and renal function if the combination is used long term or in patients with kidney disease or other potassium-raising drugs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Etodolac
- Etodolac + Ketorolac Contraindicated
- Etodolac + Ketorolac intranasal Contraindicated
- Aceclofenac + Etodolac Major
- Acemetacin + Etodolac Major
- Acetylsalicylic acid + Etodolac Major
- Alteplase + Etodolac Major
Other interactions of Potassium iodide
- Amiloride + Potassium iodide Moderate
- Amlodipine-benazepril + Potassium iodide Moderate
- Amlodipine-hydrochlorothiazide-valsartan + Potassium iodide Moderate
- Amlodipine-olmesartan-hydrochlorothiazide + Potassium iodide Moderate
- Amlodipine-olmesartan + Potassium iodide Moderate
- Amlodipine-perindopril + Potassium iodide Moderate
Frequently asked questions
Can I take Etodolac with Potassium iodide?
MediHelp rates the interaction as minor. Etodolac and Potassium iodide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Potassium iodide supplies a potassium load, and NSAIDs can reduce renal potassium excretion. Together they may raise serum potassium, particularly in patients with renal impairment or other risk factors for hyperkalemia.
How serious is the interaction between Etodolac and Potassium iodide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check serum potassium and renal function if the combination is used long term or in patients with kidney disease or other potassium-raising drugs.
What other medicines interact with Etodolac?
MediHelp also lists interactions of Etodolac with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Etodolac page.
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