Drug interactions
Everolimus + Trastuzumab
Severity: Moderate
Everolimus and Trastuzumab: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Everolimus is immunosuppressive and trastuzumab increases neutropenia risk when combined with myelosuppressive therapy. Combined use may increase infection risk.
What this interaction means in plain words
Everolimus and Trastuzumab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Everolimus belongs to Oncology; Trastuzumab belongs to Oncology.
Why it happens
Additive immunosuppressive and myelosuppressive effects.
What to do
Monitor blood counts and watch for infection. Manage neutropenia according to oncology protocols.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Everolimus
- Bcg vaccine live + Everolimus Contraindicated
- Everolimus + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Everolimus + Levoketoconazole Contraindicated
- Everolimus + Measles mumps and rubella vaccine live Contraindicated
- Everolimus + Measles mumps rubella and varicella vaccine live Contraindicated
- Everolimus + Measles vaccine Contraindicated
Other interactions of Trastuzumab
Frequently asked questions
Can I take Everolimus with Trastuzumab?
MediHelp rates the interaction as moderate. Everolimus and Trastuzumab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Everolimus is immunosuppressive and trastuzumab increases neutropenia risk when combined with myelosuppressive therapy. Combined use may increase infection risk.
How serious is the interaction between Everolimus and Trastuzumab?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood counts and watch for infection. Manage neutropenia according to oncology protocols.
What other medicines interact with Everolimus?
MediHelp also lists interactions of Everolimus with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Levoketoconazole. The full list is on the Everolimus page.
Full monographs, dosing and an interaction checker in the MediHelp app
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