Drug interactions
Felodipine + Labetalol
Severity: Minor
Felodipine and Labetalol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Felodipine and labetalol lower blood pressure additively. Hypotension may occur at initiation, though the combination is often used intentionally.
What this interaction means in plain words
Felodipine and Labetalol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Felodipine belongs to Cardiovascular; Labetalol belongs to Cardiovascular.
Why it happens
Additive vasodilation and antihypertensive effects via different mechanisms.
What to do
Monitor blood pressure and adjust doses gradually.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Labetalol
- Amifostine + Labetalol Major
- Amiodarone + Labetalol Major
- Atenolol-chlorthalidone + Labetalol Major
- Atenolol + Labetalol Major
- Betaxolol + Labetalol Major
- Bisoprolol + Labetalol Major
Other interactions of Felodipine
- Felodipine + Itraconazole Contraindicated
- Aldesleukin + Felodipine Major
- Amifostine + Felodipine Major
- Apalutamide + Felodipine Major
- Atazanavir + Felodipine Major
- Carbamazepine + Felodipine Major
Frequently asked questions
Can I take Felodipine with Labetalol?
MediHelp rates the interaction as minor. Felodipine and Labetalol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Felodipine and labetalol lower blood pressure additively. Hypotension may occur at initiation, though the combination is often used intentionally.
How serious is the interaction between Felodipine and Labetalol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and adjust doses gradually.
What other medicines interact with Labetalol?
MediHelp also lists interactions of Labetalol with, for example, Amifostine, Amiodarone, Atenolol-chlorthalidone. The full list is on the Labetalol page.
Full monographs, dosing and an interaction checker in the MediHelp app
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