Drug interactions
Felodipine + Metoprolol
Severity: Minor
Felodipine and Metoprolol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Felodipine is a dihydropyridine vasodilator often combined with beta-blockers, and the combination lowers blood pressure more than either drug alone. Excess hypotension or dizziness can occur, but the combination is commonly used effectively.
What this interaction means in plain words
Felodipine and Metoprolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Felodipine belongs to Cardiovascular; Metoprolol belongs to Cardiovascular.
Why it happens
Additive blood pressure lowering from vasodilation (calcium channel blockade) and beta-1 blockade.
What to do
Monitor blood pressure and heart rate when starting or titrating either drug. Adjust doses if symptomatic hypotension develops.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Metoprolol
- Metoprolol + Thioridazine Contraindicated
- Amifostine + Metoprolol Major
- Amiodarone + Metoprolol Major
- Atenolol-chlorthalidone + Metoprolol Major
- Atenolol + Metoprolol Major
- Betaxolol + Metoprolol Major
Other interactions of Felodipine
- Felodipine + Itraconazole Contraindicated
- Aldesleukin + Felodipine Major
- Amifostine + Felodipine Major
- Apalutamide + Felodipine Major
- Atazanavir + Felodipine Major
- Carbamazepine + Felodipine Major
Frequently asked questions
Can I take Felodipine with Metoprolol?
MediHelp rates the interaction as minor. Felodipine and Metoprolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Felodipine is a dihydropyridine vasodilator often combined with beta-blockers, and the combination lowers blood pressure more than either drug alone. Excess hypotension or dizziness can occur, but the combination is commonly used effectively.
How serious is the interaction between Felodipine and Metoprolol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate when starting or titrating either drug. Adjust doses if symptomatic hypotension develops.
What other medicines interact with Metoprolol?
MediHelp also lists interactions of Metoprolol with, for example, Thioridazine, Amifostine, Amiodarone. The full list is on the Metoprolol page.
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