Drug interactions
Fenofibric acid + Insulin lispro
Severity: Minor
Fenofibric acid and Insulin lispro: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Fenofibric acid may modestly improve insulin sensitivity, so insulin requirements can fall when it is added. This can lead to hypoglycemia if the insulin dose is not adjusted. The effect is generally small and manageable.
What this interaction means in plain words
Fenofibric acid and Insulin lispro have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Fenofibric acid belongs to Cardiovascular; Insulin lispro belongs to Endocrine.
Why it happens
Additive glucose-lowering pharmacodynamic effect through improved insulin sensitivity; the mechanism is not firmly established.
What to do
Monitor blood glucose when starting or stopping fenofibric acid and reduce the insulin lispro dose if hypoglycemia occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Fenofibric acid
- Atorvastatin + Fenofibric acid Moderate
- Chlorpropamide + Fenofibric acid Moderate
- Cholestyramine + Fenofibric acid Moderate
- Cholic acid + Fenofibric acid Moderate
- Colchicine + Fenofibric acid Moderate
- Colestipol + Fenofibric acid Moderate
Other interactions of Insulin lispro
Frequently asked questions
Can I take Fenofibric acid with Insulin lispro?
MediHelp rates the interaction as minor. Fenofibric acid and Insulin lispro have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Fenofibric acid may modestly improve insulin sensitivity, so insulin requirements can fall when it is added. This can lead to hypoglycemia if the insulin dose is not adjusted. The effect is generally small and manageable.
How serious is the interaction between Fenofibric acid and Insulin lispro?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when starting or stopping fenofibric acid and reduce the insulin lispro dose if hypoglycemia occurs.
What other medicines interact with Fenofibric acid?
MediHelp also lists interactions of Fenofibric acid with, for example, Atorvastatin, Chlorpropamide, Cholestyramine. The full list is on the Fenofibric acid page.
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