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Drug interactions

Ferric maltol + Ibandronate

Severity: Moderate

Ferric maltol and Ibandronate: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Oral iron can chelate ibandronate in the gut and lower its absorption, potentially reducing its efficacy.

What this interaction means in plain words

Ferric maltol and Ibandronate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Ferric maltol belongs to Miscellaneous; Ibandronate belongs to Musculoskeletal.

Evidence level: Low

Why it happens

Chelation of ibandronate by polyvalent iron cations in the GI tract reduces absorption.

What to do

Take oral ibandronate with plain water after fasting and delay ferric maltol for at least 60 minutes.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Ferric maltol with Ibandronate?

MediHelp rates the interaction as moderate. Ferric maltol and Ibandronate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral iron can chelate ibandronate in the gut and lower its absorption, potentially reducing its efficacy.

How serious is the interaction between Ferric maltol and Ibandronate?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take oral ibandronate with plain water after fasting and delay ferric maltol for at least 60 minutes.

What other medicines interact with Ibandronate?

MediHelp also lists interactions of Ibandronate with, for example, Aluminum hydroxide, Calcium acetate, Calcium carbonate. The full list is on the Ibandronate page.

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