Drug interactions
Ferric maltol + Ofloxacin
Severity: Moderate
Ferric maltol and Ofloxacin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oral ferric iron can bind ofloxacin in the gut, reducing its absorption and possibly causing treatment failure. The effect depends on both drugs being taken by mouth at similar times.
What this interaction means in plain words
Ferric maltol and Ofloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Ferric maltol belongs to Miscellaneous; Ofloxacin belongs to Anti Bacterial.
Why it happens
Chelation of ofloxacin by iron in the gastrointestinal tract, reducing absorption.
What to do
Take ofloxacin at least 2 hours before or after ferric maltol. Monitor the clinical response to the antibiotic.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ofloxacin
- Ofloxacin + Thioridazine Contraindicated
- Adagrasib + Ofloxacin Major
- Amiodarone + Ofloxacin Major
- Amisulpride + Ofloxacin Major
- Anagrelide + Ofloxacin Major
- Arsenic trioxide + Ofloxacin Major
Other interactions of Ferric maltol
- Aluminum hydroxide + Ferric maltol Moderate
- Calcium carbonate + Ferric maltol Moderate
- Calcium + Ferric maltol Moderate
- Carbidopa-entacapone-levodopa + Ferric maltol Moderate
- Carbidopa-levodopa + Ferric maltol Moderate
- Cimetidine + Ferric maltol Moderate
Frequently asked questions
Can I take Ferric maltol with Ofloxacin?
MediHelp rates the interaction as moderate. Ferric maltol and Ofloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral ferric iron can bind ofloxacin in the gut, reducing its absorption and possibly causing treatment failure. The effect depends on both drugs being taken by mouth at similar times.
How serious is the interaction between Ferric maltol and Ofloxacin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take ofloxacin at least 2 hours before or after ferric maltol. Monitor the clinical response to the antibiotic.
What other medicines interact with Ofloxacin?
MediHelp also lists interactions of Ofloxacin with, for example, Thioridazine, Adagrasib, Amiodarone. The full list is on the Ofloxacin page.
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