Drug interactions
Ferric maltol + Pantoprazole
Severity: Moderate
Ferric maltol and Pantoprazole: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oral ferric maltol is absorbed better in an acidic environment, so PPIs may reduce iron uptake. Ferric maltol labeling notes less efficacy with acid suppressants, though its absorption is relatively less pH-dependent than that of other oral iron salts.
What this interaction means in plain words
Ferric maltol and Pantoprazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Ferric maltol belongs to Miscellaneous; Pantoprazole belongs to Gastrointestinal Tract.
Why it happens
Increased gastric pH reduces iron solubility and absorption.
What to do
Monitor hemoglobin and ferritin response and consider whether the PPI is still needed. Raise the iron dose or change route if the response is inadequate.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Pantoprazole
- Pantoprazole + Rilpivirine Contraindicated
- Acalabrutinib + Pantoprazole Major
- Atazanavir + Pantoprazole Major
- Dacomitinib + Pantoprazole Major
- Dasatinib + Pantoprazole Major
- Erlotinib + Pantoprazole Major
Other interactions of Ferric maltol
- Aluminum hydroxide + Ferric maltol Moderate
- Calcium carbonate + Ferric maltol Moderate
- Calcium + Ferric maltol Moderate
- Carbidopa-entacapone-levodopa + Ferric maltol Moderate
- Carbidopa-levodopa + Ferric maltol Moderate
- Cimetidine + Ferric maltol Moderate
Frequently asked questions
Can I take Ferric maltol with Pantoprazole?
MediHelp rates the interaction as moderate. Ferric maltol and Pantoprazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral ferric maltol is absorbed better in an acidic environment, so PPIs may reduce iron uptake. Ferric maltol labeling notes less efficacy with acid suppressants, though its absorption is relatively less pH-dependent than that of other oral iron salts.
How serious is the interaction between Ferric maltol and Pantoprazole?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor hemoglobin and ferritin response and consider whether the PPI is still needed. Raise the iron dose or change route if the response is inadequate.
What other medicines interact with Pantoprazole?
MediHelp also lists interactions of Pantoprazole with, for example, Rilpivirine, Acalabrutinib, Atazanavir. The full list is on the Pantoprazole page.
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