Drug interactions
Ferrous sulfate + Manganese
Severity: Minor
Ferrous sulfate and Manganese: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Iron and manganese share intestinal absorption pathways, so high iron intake can lower manganese absorption. The effect is generally small and rarely clinically relevant except with long-term supplementation.
What this interaction means in plain words
Ferrous sulfate and Manganese have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Ferrous sulfate belongs to Miscellaneous; Manganese belongs to Gastrointestinal Tract.
Why it happens
Competition for shared intestinal divalent metal transporter uptake.
What to do
Usually no action needed; separate doses by a couple of hours if both supplements are taken, and review manganese status in long-term parenteral or supplemental use.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ferrous sulfate
Other interactions of Manganese
- Delafloxacin + Manganese Moderate
- Manganese + Omadacycline Moderate
- Manganese + Sarecycline Moderate
- Baloxavir marboxil + Manganese Minor
- Calcium acetate + Manganese Minor
- Calcium carbonate + Manganese Minor
Frequently asked questions
Can I take Ferrous sulfate with Manganese?
MediHelp rates the interaction as minor. Ferrous sulfate and Manganese have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Iron and manganese share intestinal absorption pathways, so high iron intake can lower manganese absorption. The effect is generally small and rarely clinically relevant except with long-term supplementation.
How serious is the interaction between Ferrous sulfate and Manganese?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Usually no action needed; separate doses by a couple of hours if both supplements are taken, and review manganese status in long-term parenteral or supplemental use.
What other medicines interact with Ferrous sulfate?
MediHelp also lists interactions of Ferrous sulfate with, for example, Ciprofloxacin, Dimercaprol, Acetohydroxamic acid. The full list is on the Ferrous sulfate page.
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