Drug interactions
Baloxavir marboxil + Manganese
Severity: Minor
Baloxavir marboxil and Manganese: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Baloxavir may chelate polyvalent cations like manganese in the gut, potentially lowering absorption. The data are largely extrapolated from animal studies with other cations.
What this interaction means in plain words
Baloxavir marboxil and Manganese have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Baloxavir marboxil belongs to Anti Virals; Manganese belongs to Gastrointestinal Tract.
Why it happens
Chelation with polyvalent cations in the GI tract may reduce baloxavir absorption.
What to do
Separate baloxavir from manganese supplements by at least 2 hours, or defer the supplement during the short treatment course.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Manganese
- Delafloxacin + Manganese Moderate
- Manganese + Omadacycline Moderate
- Manganese + Sarecycline Moderate
- Calcium acetate + Manganese Minor
- Calcium carbonate + Manganese Minor
- Calcium chloride + Manganese Minor
Other interactions of Baloxavir marboxil
- Aluminum hydroxide + Baloxavir marboxil Moderate
- Baloxavir marboxil + Calcium Moderate
- Baloxavir marboxil + Calcium carbonate Moderate
- Baloxavir marboxil + Carbonyl iron Moderate
- Baloxavir marboxil + Ferrous fumarate Moderate
- Baloxavir marboxil + Ferrous gluconate Moderate
Frequently asked questions
Can I take Baloxavir marboxil with Manganese?
MediHelp rates the interaction as minor. Baloxavir marboxil and Manganese have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Baloxavir may chelate polyvalent cations like manganese in the gut, potentially lowering absorption. The data are largely extrapolated from animal studies with other cations.
How serious is the interaction between Baloxavir marboxil and Manganese?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate baloxavir from manganese supplements by at least 2 hours, or defer the supplement during the short treatment course.
What other medicines interact with Manganese?
MediHelp also lists interactions of Manganese with, for example, Delafloxacin, Omadacycline, Sarecycline. The full list is on the Manganese page.
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