Drug interactions
Fesoterodine + Tiotropium-olodaterol
Severity: Moderate
Fesoterodine and Tiotropium-olodaterol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both fesoterodine and tiotropium are antimuscarinic agents, so their effects add together. This may produce dry mouth, constipation, urinary retention, blurred vision and confusion.
What this interaction means in plain words
Fesoterodine and Tiotropium-olodaterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Fesoterodine belongs to Genitourinary; Tiotropium-olodaterol belongs to Respiratory.
Why it happens
Additive muscarinic receptor antagonism.
What to do
Monitor for anticholinergic adverse effects, especially in older patients. Reduce the dose or choose an alternative if symptoms become troublesome.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Tiotropium-olodaterol
Other interactions of Fesoterodine
Frequently asked questions
Can I take Fesoterodine with Tiotropium-olodaterol?
MediHelp rates the interaction as moderate. Fesoterodine and Tiotropium-olodaterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both fesoterodine and tiotropium are antimuscarinic agents, so their effects add together. This may produce dry mouth, constipation, urinary retention, blurred vision and confusion.
How serious is the interaction between Fesoterodine and Tiotropium-olodaterol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for anticholinergic adverse effects, especially in older patients. Reduce the dose or choose an alternative if symptoms become troublesome.
What other medicines interact with Tiotropium-olodaterol?
MediHelp also lists interactions of Tiotropium-olodaterol with, for example, Amisulpride, Arformoterol, Arsenic trioxide. The full list is on the Tiotropium-olodaterol page.
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