Drug interactions
Finasteride + Griseofulvin
Severity: Minor
Finasteride and Griseofulvin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Griseofulvin is a modest CYP3A4 inducer and could in theory lower finasteride exposure. Finasteride has a wide therapeutic margin, so any loss of effect is unlikely to matter clinically.
What this interaction means in plain words
Finasteride and Griseofulvin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Finasteride belongs to Genitourinary; Griseofulvin belongs to Anti Fungals.
Why it happens
Induction of CYP3A4 by griseofulvin may increase the hepatic metabolism of finasteride.
What to do
No dose change is needed. If reduced response to finasteride is suspected during prolonged griseofulvin therapy, reassess symptoms and PSA or hair response.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Finasteride
- Finasteride + Levoketoconazole Moderate
- Finasteride + Nefazodone Moderate
- Finasteride + Rifampin Moderate
- Finasteride + St john's wort Moderate
- Amobarbital + Finasteride Minor
- Aprepitant + Finasteride Minor
Other interactions of Griseofulvin
Frequently asked questions
Can I take Finasteride with Griseofulvin?
MediHelp rates the interaction as minor. Finasteride and Griseofulvin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Griseofulvin is a modest CYP3A4 inducer and could in theory lower finasteride exposure. Finasteride has a wide therapeutic margin, so any loss of effect is unlikely to matter clinically.
How serious is the interaction between Finasteride and Griseofulvin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is needed. If reduced response to finasteride is suspected during prolonged griseofulvin therapy, reassess symptoms and PSA or hair response.
What other medicines interact with Finasteride?
MediHelp also lists interactions of Finasteride with, for example, Levoketoconazole, Nefazodone, Rifampin. The full list is on the Finasteride page.
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