Drug interactions
Finasteride + Rifabutin
Severity: Minor
Finasteride and Rifabutin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Rifabutin is a CYP3A4 inducer and may reduce finasteride exposure. The effect is weaker than with rifampicin and is of limited clinical relevance.
What this interaction means in plain words
Finasteride and Rifabutin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Finasteride belongs to Genitourinary; Rifabutin belongs to Anti Bacterial.
Why it happens
Rifabutin induces CYP3A4, accelerating finasteride clearance.
What to do
No routine adjustment is needed. Review therapeutic response to finasteride during extended rifabutin therapy.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Finasteride
- Finasteride + Levoketoconazole Moderate
- Finasteride + Nefazodone Moderate
- Finasteride + Rifampin Moderate
- Finasteride + St john's wort Moderate
- Amobarbital + Finasteride Minor
- Aprepitant + Finasteride Minor
Other interactions of Rifabutin
- Cabotegravir + Rifabutin Contraindicated
- Lorlatinib + Rifabutin Contraindicated
- Rifabutin + Voriconazole Contraindicated
- Apixaban + Rifabutin Major
- Axitinib + Rifabutin Major
- Brexpiprazole + Rifabutin Major
Frequently asked questions
Can I take Finasteride with Rifabutin?
MediHelp rates the interaction as minor. Finasteride and Rifabutin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Rifabutin is a CYP3A4 inducer and may reduce finasteride exposure. The effect is weaker than with rifampicin and is of limited clinical relevance.
How serious is the interaction between Finasteride and Rifabutin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is needed. Review therapeutic response to finasteride during extended rifabutin therapy.
What other medicines interact with Finasteride?
MediHelp also lists interactions of Finasteride with, for example, Levoketoconazole, Nefazodone, Rifampin. The full list is on the Finasteride page.
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