Drug interactions
Finerenone + Vinorelbine
Severity: Minor
Finerenone and Vinorelbine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Vinorelbine is a CYP3A4 substrate and is not recognized as a meaningful CYP3A4 inhibitor, so a rise in finerenone exposure is unlikely. Any interaction is theoretical.
What this interaction means in plain words
Finerenone and Vinorelbine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Finerenone belongs to Cardiovascular; Vinorelbine belongs to Oncology.
Why it happens
Competition for CYP3A4 metabolism is postulated, but clinically relevant inhibition has not been established.
What to do
Monitor serum potassium and renal function as usual during finerenone therapy. No dose change is needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Vinorelbine
Other interactions of Finerenone
- Carbamazepine + Finerenone Contraindicated
- Clarithromycin + Finerenone Contraindicated
- Ensitrelvir + Finerenone Contraindicated
- Finerenone + Itraconazole Contraindicated
- Finerenone + Ketoconazole Contraindicated
- Finerenone + Posaconazole Contraindicated
Frequently asked questions
Can I take Finerenone with Vinorelbine?
MediHelp rates the interaction as minor. Finerenone and Vinorelbine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Vinorelbine is a CYP3A4 substrate and is not recognized as a meaningful CYP3A4 inhibitor, so a rise in finerenone exposure is unlikely. Any interaction is theoretical.
How serious is the interaction between Finerenone and Vinorelbine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium and renal function as usual during finerenone therapy. No dose change is needed.
What other medicines interact with Vinorelbine?
MediHelp also lists interactions of Vinorelbine with, for example, Adenovirus types 4 and 7 live, Apalutamide, Belatacept. The full list is on the Vinorelbine page.
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