Drug interactions
Fingolimod + Indacaterol
Severity: Moderate
Fingolimod and Indacaterol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Fingolimod causes bradycardia after the first dose and has been linked to QT prolongation, while indacaterol can add to arrhythmic risk. The combination may increase the chance of significant rhythm disturbances.
What this interaction means in plain words
Fingolimod and Indacaterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Fingolimod belongs to Central Nervous System; Indacaterol belongs to Respiratory.
Why it happens
Additive pharmacodynamic effects on cardiac conduction and QT interval.
What to do
Perform first-dose cardiac monitoring as recommended for fingolimod and check ECG in patients on QT-prolonging drugs. Keep potassium and magnesium normal.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Indacaterol
Other interactions of Fingolimod
- Adenovirus types 4 and 7 live + Fingolimod Contraindicated
- Bcg vaccine live + Fingolimod Contraindicated
- Fingolimod + Pimozide Contraindicated
- Fingolimod + Ponesimod Contraindicated
- Fingolimod + Quinidine Contraindicated
- Fingolimod + Siponimod Contraindicated
Frequently asked questions
Can I take Fingolimod with Indacaterol?
MediHelp rates the interaction as moderate. Fingolimod and Indacaterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Fingolimod causes bradycardia after the first dose and has been linked to QT prolongation, while indacaterol can add to arrhythmic risk. The combination may increase the chance of significant rhythm disturbances.
How serious is the interaction between Fingolimod and Indacaterol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Perform first-dose cardiac monitoring as recommended for fingolimod and check ECG in patients on QT-prolonging drugs. Keep potassium and magnesium normal.
What other medicines interact with Indacaterol?
MediHelp also lists interactions of Indacaterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Indacaterol page.
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