Drug interactions
Fingolimod + Triclabendazole
Severity: Moderate
Fingolimod and Triclabendazole: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Triclabendazole can prolong the QT interval, and fingolimod can cause bradycardia and heart rate effects. Using them together may increase the risk of arrhythmia in vulnerable patients.
What this interaction means in plain words
Fingolimod and Triclabendazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Fingolimod belongs to Central Nervous System; Triclabendazole belongs to Anti Parasitic.
Why it happens
Additive QT prolongation with bradycardia as a risk amplifier.
What to do
Obtain a baseline ECG in patients with cardiac risk factors and correct electrolytes. Monitor ECG during the short triclabendazole course.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Fingolimod
- Adenovirus types 4 and 7 live + Fingolimod Contraindicated
- Bcg vaccine live + Fingolimod Contraindicated
- Fingolimod + Pimozide Contraindicated
- Fingolimod + Ponesimod Contraindicated
- Fingolimod + Quinidine Contraindicated
- Fingolimod + Siponimod Contraindicated
Other interactions of Triclabendazole
Frequently asked questions
Can I take Fingolimod with Triclabendazole?
MediHelp rates the interaction as moderate. Fingolimod and Triclabendazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Triclabendazole can prolong the QT interval, and fingolimod can cause bradycardia and heart rate effects. Using them together may increase the risk of arrhythmia in vulnerable patients.
How serious is the interaction between Fingolimod and Triclabendazole?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain a baseline ECG in patients with cardiac risk factors and correct electrolytes. Monitor ECG during the short triclabendazole course.
What other medicines interact with Fingolimod?
MediHelp also lists interactions of Fingolimod with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Pimozide. The full list is on the Fingolimod page.
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