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Drug interactions

Flavoxate + Glycopyrronium

Severity: Moderate

Flavoxate and Glycopyrronium: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Flavoxate has antimuscarinic properties, so adding glycopyrronium can intensify anticholinergic effects such as dry mouth, blurred vision, constipation, tachycardia and urinary retention.

What this interaction means in plain words

Flavoxate and Glycopyrronium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Flavoxate belongs to Genitourinary; Glycopyrronium belongs to Respiratory.

Evidence level: Low

Why it happens

Additive antimuscarinic pharmacodynamic effects.

What to do

Monitor for anticholinergic adverse effects and avoid prolonged concurrent use where an alternative is available.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Flavoxate with Glycopyrronium?

MediHelp rates the interaction as moderate. Flavoxate and Glycopyrronium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Flavoxate has antimuscarinic properties, so adding glycopyrronium can intensify anticholinergic effects such as dry mouth, blurred vision, constipation, tachycardia and urinary retention.

How serious is the interaction between Flavoxate and Glycopyrronium?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for anticholinergic adverse effects and avoid prolonged concurrent use where an alternative is available.

What other medicines interact with Glycopyrronium?

MediHelp also lists interactions of Glycopyrronium with, for example, Clozapine, Abobotulinumtoxina, Aclidinium. The full list is on the Glycopyrronium page.

Full monographs, dosing and an interaction checker in the MediHelp app

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