Drug interactions
Flibanserin + Nizatidine
Severity: Minor
Flibanserin and Nizatidine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Nizatidine is not a recognized CYP3A4 inhibitor, so a meaningful rise in flibanserin levels is not expected. The legacy concern relates to CYP3A4 inhibitors, which does not apply to nizatidine.
What this interaction means in plain words
Flibanserin and Nizatidine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Flibanserin belongs to Genitourinary; Nizatidine belongs to Gastrointestinal Tract.
Why it happens
No established mechanism; nizatidine lacks significant CYP3A4 inhibition.
What to do
No adjustment is needed. Counsel on dizziness and sedation and avoid alcohol close to flibanserin dosing.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Nizatidine
- Atazanavir + Nizatidine Major
- Dasatinib + Nizatidine Major
- Erlotinib + Nizatidine Major
- Itraconazole + Nizatidine Major
- Ketoconazole + Nizatidine Major
- Nizatidine + Pazopanib Major
Other interactions of Flibanserin
- Atazanavir + Flibanserin Contraindicated
- Ceritinib + Flibanserin Contraindicated
- Clarithromycin + Flibanserin Contraindicated
- Cobicistat + Flibanserin Contraindicated
- Conivaptan + Flibanserin Contraindicated
- Crizotinib + Flibanserin Contraindicated
Frequently asked questions
Can I take Flibanserin with Nizatidine?
MediHelp rates the interaction as minor. Flibanserin and Nizatidine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Nizatidine is not a recognized CYP3A4 inhibitor, so a meaningful rise in flibanserin levels is not expected. The legacy concern relates to CYP3A4 inhibitors, which does not apply to nizatidine.
How serious is the interaction between Flibanserin and Nizatidine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No adjustment is needed. Counsel on dizziness and sedation and avoid alcohol close to flibanserin dosing.
What other medicines interact with Nizatidine?
MediHelp also lists interactions of Nizatidine with, for example, Atazanavir, Dasatinib, Erlotinib. The full list is on the Nizatidine page.
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