Drug interactions
Fludrocortisone + Insulin degludec-insulin aspart
Severity: Minor
Fludrocortisone and Insulin degludec-insulin aspart: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Fludrocortisone has mainly mineralocorticoid activity with some glucocorticoid effect, and may modestly raise blood glucose at higher doses. The impact on insulin requirements is usually small.
What this interaction means in plain words
Fludrocortisone and Insulin degludec-insulin aspart have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Fludrocortisone belongs to Endocrine; Insulin degludec-insulin aspart belongs to Endocrine.
Why it happens
Weak glucocorticoid activity promoting hepatic glucose output and insulin resistance.
What to do
Monitor blood glucose when starting or adjusting fludrocortisone and adjust insulin only if hyperglycemia develops.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Insulin degludec-insulin aspart
- Chlorpropamide + Insulin degludec-insulin aspart Major
- Clozapine + Insulin degludec-insulin aspart Major
- Diazoxide + Insulin degludec-insulin aspart Major
- Ethanol + Insulin degludec-insulin aspart Major
- Insulin degludec-insulin aspart + Mecasermin Major
- Insulin degludec-insulin aspart + Pioglitazone Major
Other interactions of Fludrocortisone
Frequently asked questions
Can I take Fludrocortisone with Insulin degludec-insulin aspart?
MediHelp rates the interaction as minor. Fludrocortisone and Insulin degludec-insulin aspart have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Fludrocortisone has mainly mineralocorticoid activity with some glucocorticoid effect, and may modestly raise blood glucose at higher doses. The impact on insulin requirements is usually small.
How serious is the interaction between Fludrocortisone and Insulin degludec-insulin aspart?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when starting or adjusting fludrocortisone and adjust insulin only if hyperglycemia develops.
What other medicines interact with Insulin degludec-insulin aspart?
MediHelp also lists interactions of Insulin degludec-insulin aspart with, for example, Chlorpropamide, Clozapine, Diazoxide. The full list is on the Insulin degludec-insulin aspart page.
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