Drug interactions
Fluphenazine + Levetiracetam
Severity: Minor
Fluphenazine and Levetiracetam: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Levetiracetam commonly causes somnolence and dizziness, which may add to the sedation caused by fluphenazine. Antipsychotics can also lower the seizure threshold, which is relevant in patients treated for epilepsy.
What this interaction means in plain words
Fluphenazine and Levetiracetam have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Fluphenazine belongs to Central Nervous System; Levetiracetam belongs to Central Nervous System.
Why it happens
Additive CNS depressant effects; no significant pharmacokinetic interaction is expected.
What to do
Monitor for excess drowsiness and dizziness, particularly when doses are started or increased. Review seizure control, since fluphenazine may lower the seizure threshold.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Fluphenazine
- Arsenic trioxide + Fluphenazine Contraindicated
- Dofetilide + Fluphenazine Contraindicated
- Fluphenazine + Ibutilide Contraindicated
- Fluphenazine + Pimozide Contraindicated
- Adagrasib + Fluphenazine Major
- Alfentanil + Fluphenazine Major
Other interactions of Levetiracetam
Frequently asked questions
Can I take Fluphenazine with Levetiracetam?
MediHelp rates the interaction as minor. Fluphenazine and Levetiracetam have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Levetiracetam commonly causes somnolence and dizziness, which may add to the sedation caused by fluphenazine. Antipsychotics can also lower the seizure threshold, which is relevant in patients treated for epilepsy.
How serious is the interaction between Fluphenazine and Levetiracetam?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for excess drowsiness and dizziness, particularly when doses are started or increased. Review seizure control, since fluphenazine may lower the seizure threshold.
What other medicines interact with Fluphenazine?
MediHelp also lists interactions of Fluphenazine with, for example, Arsenic trioxide, Dofetilide, Ibutilide. The full list is on the Fluphenazine page.
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