Drug interactions
Flurbiprofen + Latanoprost
Severity: Minor
Flurbiprofen and Latanoprost: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Latanoprost lowers intraocular pressure largely via prostaglandin-mediated pathways, and NSAIDs may theoretically reduce this effect, though study results are inconsistent. Clinically relevant interactions with systemic flurbiprofen are not well established.
What this interaction means in plain words
Flurbiprofen and Latanoprost have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Flurbiprofen belongs to Musculoskeletal; Latanoprost belongs to Miscellaneous.
Why it happens
Possible interference with prostaglandin-mediated aqueous outflow by cyclooxygenase inhibition; evidence is inconsistent.
What to do
No dose change is needed; monitor intraocular pressure if the patient is on concurrent NSAID therapy and control seems to change.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Flurbiprofen
- Flurbiprofen + Ketorolac Contraindicated
- Flurbiprofen + Ketorolac intranasal Contraindicated
- Aceclofenac + Flurbiprofen Major
- Acemetacin + Flurbiprofen Major
- Acetylsalicylic acid + Flurbiprofen Major
- Alteplase + Flurbiprofen Major
Other interactions of Latanoprost
- Bimatoprost + Latanoprost Moderate
- Latanoprost + Latanoprostene bunod Moderate
- Latanoprost + Tafluprost Moderate
- Latanoprost + Travoprost Moderate
- Aspirin rectal + Latanoprost Minor
- Aspirin + Latanoprost Minor
Frequently asked questions
Can I take Flurbiprofen with Latanoprost?
MediHelp rates the interaction as minor. Flurbiprofen and Latanoprost have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Latanoprost lowers intraocular pressure largely via prostaglandin-mediated pathways, and NSAIDs may theoretically reduce this effect, though study results are inconsistent. Clinically relevant interactions with systemic flurbiprofen are not well established.
How serious is the interaction between Flurbiprofen and Latanoprost?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is needed; monitor intraocular pressure if the patient is on concurrent NSAID therapy and control seems to change.
What other medicines interact with Flurbiprofen?
MediHelp also lists interactions of Flurbiprofen with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Flurbiprofen page.
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