Drug interactions
Fluticasone-salmeterol + Propylhexedrine
Severity: Minor
Fluticasone-salmeterol and Propylhexedrine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Propylhexedrine is a sympathomimetic nasal decongestant that is systemically active if misused. With salmeterol it may raise blood pressure and heart rate.
What this interaction means in plain words
Fluticasone-salmeterol and Propylhexedrine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Fluticasone-salmeterol belongs to Respiratory; Propylhexedrine belongs to Respiratory.
Why it happens
Additive sympathomimetic effects.
What to do
Use decongestant at labeled doses only and monitor blood pressure and pulse in cardiac patients.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Fluticasone-salmeterol
- Darunavir + Fluticasone-salmeterol Contraindicated
- Elvitegravir / cobicistat / emtricitabine / tenofovir df + Fluticasone-salmeterol Contraindicated
- Fluticasone-salmeterol + Fosamprenavir Contraindicated
- Fluticasone-salmeterol + Indinavir Contraindicated
- Fluticasone-salmeterol + Lopinavir Contraindicated
- Fluticasone-salmeterol + Nelfinavir Contraindicated
Other interactions of Propylhexedrine
- Isocarboxazid + Propylhexedrine Contraindicated
- Phenelzine + Propylhexedrine Contraindicated
- Linezolid + Propylhexedrine Major
- Propylhexedrine + Selegiline Major
- Propylhexedrine + Tranylcypromine Major
- Adrenaline-articaine + Propylhexedrine Moderate
Frequently asked questions
Can I take Fluticasone-salmeterol with Propylhexedrine?
MediHelp rates the interaction as minor. Fluticasone-salmeterol and Propylhexedrine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Propylhexedrine is a sympathomimetic nasal decongestant that is systemically active if misused. With salmeterol it may raise blood pressure and heart rate.
How serious is the interaction between Fluticasone-salmeterol and Propylhexedrine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use decongestant at labeled doses only and monitor blood pressure and pulse in cardiac patients.
What other medicines interact with Fluticasone-salmeterol?
MediHelp also lists interactions of Fluticasone-salmeterol with, for example, Darunavir, Elvitegravir / cobicistat / emtricitabine / tenofovir df, Fosamprenavir. The full list is on the Fluticasone-salmeterol page.
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