Drug interactions
Fluticasone-vilanterol + Gemifloxacin
Severity: Moderate
Fluticasone-vilanterol and Gemifloxacin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Gemifloxacin is a fluoroquinolone that can prolong the QT interval, and vilanterol may add to this and to cardiac stimulation. Combined use raises the risk of ventricular arrhythmia in susceptible patients.
What this interaction means in plain words
Fluticasone-vilanterol and Gemifloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Fluticasone-vilanterol belongs to Respiratory; Gemifloxacin belongs to Anti Bacterial.
Why it happens
Additive QTc prolongation with beta-agonist adrenergic and hypokalemic effects.
What to do
Consider a non-QT-prolonging antibiotic where suitable. If combined, monitor ECG and correct potassium and magnesium.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Fluticasone-vilanterol and Gemifloxacin, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Fluticasone-vilanterol
Other interactions of Gemifloxacin
- Arsenic trioxide + Gemifloxacin Contraindicated
- Dofetilide + Gemifloxacin Contraindicated
- Gemifloxacin + Ibutilide Contraindicated
- Gemifloxacin + Pimozide Contraindicated
- Gemifloxacin + Thioridazine Contraindicated
- Gemifloxacin + Vandetanib Contraindicated
Frequently asked questions
Can I take Fluticasone-vilanterol with Gemifloxacin?
MediHelp rates the interaction as moderate. Fluticasone-vilanterol and Gemifloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Gemifloxacin is a fluoroquinolone that can prolong the QT interval, and vilanterol may add to this and to cardiac stimulation. Combined use raises the risk of ventricular arrhythmia in susceptible patients.
How serious is the interaction between Fluticasone-vilanterol and Gemifloxacin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Consider a non-QT-prolonging antibiotic where suitable. If combined, monitor ECG and correct potassium and magnesium.
What other medicines interact with Fluticasone-vilanterol?
MediHelp also lists interactions of Fluticasone-vilanterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Fluticasone-vilanterol page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
