Drug interactions
Fluticasone-vilanterol + Solifenacin
Severity: Minor
Fluticasone-vilanterol and Solifenacin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Solifenacin can prolong the QT interval at supratherapeutic doses and may cause tachycardia, and vilanterol adds adrenergic cardiac effects. The risk is low at usual doses.
What this interaction means in plain words
Fluticasone-vilanterol and Solifenacin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Fluticasone-vilanterol belongs to Respiratory; Solifenacin belongs to Genitourinary.
Why it happens
Possible additive effects on heart rate and cardiac repolarization.
What to do
No routine action; check ECG and electrolytes in patients with other QT risk factors or cardiac disease.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Fluticasone-vilanterol
Other interactions of Solifenacin
Frequently asked questions
Can I take Fluticasone-vilanterol with Solifenacin?
MediHelp rates the interaction as minor. Fluticasone-vilanterol and Solifenacin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Solifenacin can prolong the QT interval at supratherapeutic doses and may cause tachycardia, and vilanterol adds adrenergic cardiac effects. The risk is low at usual doses.
How serious is the interaction between Fluticasone-vilanterol and Solifenacin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action; check ECG and electrolytes in patients with other QT risk factors or cardiac disease.
What other medicines interact with Fluticasone-vilanterol?
MediHelp also lists interactions of Fluticasone-vilanterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Fluticasone-vilanterol page.
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