Drug interactions
Fluvoxamine + Linagliptin-metformin
Severity: Minor
Fluvoxamine and Linagliptin-metformin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Fluvoxamine has been associated with changes in glycemic control, including hypoglycemia, in patients on antidiabetic drugs. The effect is variable and usually mild.
What this interaction means in plain words
Fluvoxamine and Linagliptin-metformin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Fluvoxamine belongs to Central Nervous System; Linagliptin-metformin belongs to Endocrine.
Why it happens
Possible effects on insulin sensitivity via serotonergic modulation; mechanism not firmly established.
What to do
Monitor blood glucose when starting or stopping fluvoxamine and adjust antidiabetic therapy if needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Linagliptin-metformin
Other interactions of Fluvoxamine
- Agomelatine + Fluvoxamine Contraindicated
- Alosetron + Fluvoxamine Contraindicated
- Fezolinetant + Fluvoxamine Contraindicated
- Fluvoxamine + Isocarboxazid Contraindicated
- Fluvoxamine + Mavacamten Contraindicated
- Fluvoxamine + Methylene blue Contraindicated
Frequently asked questions
Can I take Fluvoxamine with Linagliptin-metformin?
MediHelp rates the interaction as minor. Fluvoxamine and Linagliptin-metformin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Fluvoxamine has been associated with changes in glycemic control, including hypoglycemia, in patients on antidiabetic drugs. The effect is variable and usually mild.
How serious is the interaction between Fluvoxamine and Linagliptin-metformin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when starting or stopping fluvoxamine and adjust antidiabetic therapy if needed.
What other medicines interact with Linagliptin-metformin?
MediHelp also lists interactions of Linagliptin-metformin with, for example, Apalutamide, Carbamazepine, Contrast media. The full list is on the Linagliptin-metformin page.
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