Drug interactions
Fondaparinux + Sulphasalazine
Severity: Minor
Fondaparinux and Sulphasalazine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Sulfasalazine is not an anticoagulant, but rare blood dyscrasias could add to fondaparinux bleeding risk. The interaction is mostly theoretical.
What this interaction means in plain words
Fondaparinux and Sulphasalazine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Fondaparinux belongs to Cardiovascular; Sulphasalazine belongs to Gastrointestinal Tract.
Why it happens
No direct mechanism; possible additive bleeding risk if sulfasalazine causes cytopenias.
What to do
Monitor platelet count and hemoglobin and watch for bleeding.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Sulphasalazine
- Deferiprone + Sulphasalazine Major
- Pexidartinib + Sulphasalazine Major
- Sepiapterin + Sulphasalazine Major
- Acalabrutinib + Sulphasalazine Moderate
- Aceclofenac + Sulphasalazine Moderate
- Asciminib + Sulphasalazine Moderate
Other interactions of Fondaparinux
- Defibrotide + Fondaparinux Contraindicated
- Fondaparinux + Ketorolac Contraindicated
- Abciximab + Fondaparinux Major
- Aceclofenac + Fondaparinux Major
- Acetylsalicylic acid + Fondaparinux Major
- Alteplase + Fondaparinux Major
Frequently asked questions
Can I take Fondaparinux with Sulphasalazine?
MediHelp rates the interaction as minor. Fondaparinux and Sulphasalazine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Sulfasalazine is not an anticoagulant, but rare blood dyscrasias could add to fondaparinux bleeding risk. The interaction is mostly theoretical.
How serious is the interaction between Fondaparinux and Sulphasalazine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor platelet count and hemoglobin and watch for bleeding.
What other medicines interact with Sulphasalazine?
MediHelp also lists interactions of Sulphasalazine with, for example, Deferiprone, Pexidartinib, Sepiapterin. The full list is on the Sulphasalazine page.
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