Drug interactions
Formoterol + Posaconazole
Severity: Moderate
Formoterol and Posaconazole: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Posaconazole is associated with QT prolongation and formoterol can add QTc effects, tachycardia and hypokalemia. The combination may raise the risk of torsades de pointes, especially in patients with hypokalemia or cardiac disease.
What this interaction means in plain words
Formoterol and Posaconazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Formoterol belongs to Respiratory; Posaconazole belongs to Anti Fungals.
Why it happens
Additive QT prolongation with beta2-agonist-induced hypokalemia.
What to do
Check and correct potassium and magnesium, obtain a baseline ECG in at-risk patients, and monitor for palpitations or syncope.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Formoterol
- Adagrasib + Formoterol Major
- Amiodarone + Formoterol Major
- Amisulpride + Formoterol Major
- Amitriptyline + Formoterol Major
- Amoxapine + Formoterol Major
- Arformoterol + Formoterol Major
Other interactions of Posaconazole
- Artemether + Posaconazole Contraindicated
- Avanafil + Posaconazole Contraindicated
- Cobimetinib + Posaconazole Contraindicated
- Conivaptan + Posaconazole Contraindicated
- Dihydroergotamine intranasal + Posaconazole Contraindicated
- Dihydroergotamine + Posaconazole Contraindicated
Frequently asked questions
Can I take Formoterol with Posaconazole?
MediHelp rates the interaction as moderate. Formoterol and Posaconazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Posaconazole is associated with QT prolongation and formoterol can add QTc effects, tachycardia and hypokalemia. The combination may raise the risk of torsades de pointes, especially in patients with hypokalemia or cardiac disease.
How serious is the interaction between Formoterol and Posaconazole?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check and correct potassium and magnesium, obtain a baseline ECG in at-risk patients, and monitor for palpitations or syncope.
What other medicines interact with Formoterol?
MediHelp also lists interactions of Formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Formoterol page.
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