Drug interactions
Formoterol-mometasone + Moxifloxacin
Severity: Moderate
Formoterol-mometasone and Moxifloxacin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Fluoroquinolones and corticosteroids are each associated with tendinopathy, and combined use raises the risk of tendon inflammation or rupture, mainly with systemic steroids and in older patients. With inhaled mometasone the systemic exposure is low, so the added risk is small. Moxifloxacin and formoterol can also both prolong the QTc interval.
What this interaction means in plain words
Formoterol-mometasone and Moxifloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Formoterol-mometasone belongs to Respiratory; Moxifloxacin belongs to Anti Bacterial.
Why it happens
Additive tendon toxicity from fluoroquinolones and corticosteroids, plus additive QT prolongation of moxifloxacin and formoterol.
What to do
Counsel patients to stop moxifloxacin and report tendon pain or swelling promptly. Consider ECG monitoring and correction of potassium in patients with QT risk factors.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Formoterol-mometasone and Moxifloxacin, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Formoterol-mometasone
Other interactions of Moxifloxacin
- Amiodarone + Moxifloxacin Contraindicated
- Arsenic trioxide + Moxifloxacin Contraindicated
- Disopyramide + Moxifloxacin Contraindicated
- Dofetilide + Moxifloxacin Contraindicated
- Dronedarone + Moxifloxacin Contraindicated
- Droperidol + Moxifloxacin Contraindicated
Frequently asked questions
Can I take Formoterol-mometasone with Moxifloxacin?
MediHelp rates the interaction as moderate. Formoterol-mometasone and Moxifloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Fluoroquinolones and corticosteroids are each associated with tendinopathy, and combined use raises the risk of tendon inflammation or rupture, mainly with systemic steroids and in older patients. With inhaled mometasone the systemic exposure is low, so the added risk is small. Moxifloxacin and formoterol can also both prolong the QTc interval.
How serious is the interaction between Formoterol-mometasone and Moxifloxacin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel patients to stop moxifloxacin and report tendon pain or swelling promptly. Consider ECG monitoring and correction of potassium in patients with QT risk factors.
What other medicines interact with Formoterol-mometasone?
MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
