Drug interactions
Formoterol-mometasone + Osilodrostat
Severity: Moderate
Formoterol-mometasone and Osilodrostat: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Osilodrostat can prolong the QTc interval and formoterol may also affect QT and lower potassium. The combination may raise the risk of arrhythmia, especially with electrolyte disturbances.
What this interaction means in plain words
Formoterol-mometasone and Osilodrostat can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Formoterol-mometasone belongs to Respiratory; Osilodrostat belongs to Endocrine.
Why it happens
Additive QTc prolongation, with formoterol-induced hypokalemia as a contributing factor.
What to do
Obtain a baseline ECG and monitor QTc, potassium and magnesium, correcting abnormalities before and during co-therapy.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Formoterol-mometasone and Osilodrostat, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Formoterol-mometasone
Other interactions of Osilodrostat
Frequently asked questions
Can I take Formoterol-mometasone with Osilodrostat?
MediHelp rates the interaction as moderate. Formoterol-mometasone and Osilodrostat can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Osilodrostat can prolong the QTc interval and formoterol may also affect QT and lower potassium. The combination may raise the risk of arrhythmia, especially with electrolyte disturbances.
How serious is the interaction between Formoterol-mometasone and Osilodrostat?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain a baseline ECG and monitor QTc, potassium and magnesium, correcting abnormalities before and during co-therapy.
What other medicines interact with Formoterol-mometasone?
MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
