Drug interactions
Formoterol-mometasone + Osimertinib
Severity: Moderate
Formoterol-mometasone and Osimertinib: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Osimertinib is associated with QTc prolongation, and formoterol can contribute to QT effects and hypokalemia. Combined use may raise the risk of ventricular arrhythmia.
What this interaction means in plain words
Formoterol-mometasone and Osimertinib can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Formoterol-mometasone belongs to Respiratory; Osimertinib belongs to Oncology.
Why it happens
Additive QTc prolongation, with beta-agonist related hypokalemia.
What to do
Perform periodic ECG monitoring and check electrolytes, correcting potassium and magnesium deficits; stop or adjust therapy if QTc becomes markedly prolonged.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Formoterol-mometasone
Other interactions of Osimertinib
Frequently asked questions
Can I take Formoterol-mometasone with Osimertinib?
MediHelp rates the interaction as moderate. Formoterol-mometasone and Osimertinib can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Osimertinib is associated with QTc prolongation, and formoterol can contribute to QT effects and hypokalemia. Combined use may raise the risk of ventricular arrhythmia.
How serious is the interaction between Formoterol-mometasone and Osimertinib?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Perform periodic ECG monitoring and check electrolytes, correcting potassium and magnesium deficits; stop or adjust therapy if QTc becomes markedly prolonged.
What other medicines interact with Formoterol-mometasone?
MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.
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