Drug interactions
Formoterol-mometasone + Paliperidone
Severity: Moderate
Formoterol-mometasone and Paliperidone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both formoterol and paliperidone can prolong the QT interval, and beta-agonist-induced hypokalemia may add to arrhythmia risk. The combination may raise the chance of QT-related ventricular arrhythmias, particularly in patients with other risk factors.
What this interaction means in plain words
Formoterol-mometasone and Paliperidone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Formoterol-mometasone belongs to Respiratory; Paliperidone belongs to Central Nervous System.
Why it happens
Additive QTc prolongation, with possible beta-2-agonist-mediated hypokalemia and tachycardia contributing to proarrhythmic risk.
What to do
Check baseline ECG and electrolytes in patients with cardiac risk factors and correct potassium and magnesium. Use the lowest effective formoterol dose and watch for palpitations or syncope.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Formoterol-mometasone
Other interactions of Paliperidone
- Ibutilide + Paliperidone Contraindicated
- Paliperidone + Pimozide Contraindicated
- Paliperidone + Vandetanib Contraindicated
- Adagrasib + Paliperidone Major
- Amiodarone + Paliperidone Major
- Amisulpride + Paliperidone Major
Frequently asked questions
Can I take Formoterol-mometasone with Paliperidone?
MediHelp rates the interaction as moderate. Formoterol-mometasone and Paliperidone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both formoterol and paliperidone can prolong the QT interval, and beta-agonist-induced hypokalemia may add to arrhythmia risk. The combination may raise the chance of QT-related ventricular arrhythmias, particularly in patients with other risk factors.
How serious is the interaction between Formoterol-mometasone and Paliperidone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check baseline ECG and electrolytes in patients with cardiac risk factors and correct potassium and magnesium. Use the lowest effective formoterol dose and watch for palpitations or syncope.
What other medicines interact with Formoterol-mometasone?
MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.
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