Drug interactions
Foscarnet + Ozanimod
Severity: Moderate
Foscarnet and Ozanimod: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ozanimod can slow heart rate and AV conduction at initiation. Foscarnet may prolong QT and cause electrolyte abnormalities, so bradycardia could increase the risk of torsades de pointes. Labeling advises against starting ozanimod in patients taking QT-prolonging drugs with arrhythmic potential without cardiology advice.
What this interaction means in plain words
Foscarnet and Ozanimod can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Foscarnet belongs to Anti Virals; Ozanimod belongs to Central Nervous System.
Why it happens
Ozanimod-related bradycardia combined with foscarnet-related QT prolongation and electrolyte disturbance.
What to do
Obtain an ECG before starting ozanimod and seek cardiology advice if foscarnet is ongoing. Monitor heart rate, QTc and electrolytes.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Foscarnet
- Cidofovir + Foscarnet Contraindicated
- Foscarnet + Pimozide Contraindicated
- Foscarnet + Thioridazine Contraindicated
- Foscarnet + Vandetanib Contraindicated
- Adagrasib + Foscarnet Major
- Adefovir + Foscarnet Major
Other interactions of Ozanimod
- Isocarboxazid + Ozanimod Contraindicated
- Linezolid + Ozanimod Contraindicated
- Ozanimod + Phenelzine Contraindicated
- Ozanimod + Procarbazine Contraindicated
- Ozanimod + Rasagiline Contraindicated
- Ozanimod + Safinamide Contraindicated
Frequently asked questions
Can I take Foscarnet with Ozanimod?
MediHelp rates the interaction as moderate. Foscarnet and Ozanimod can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ozanimod can slow heart rate and AV conduction at initiation. Foscarnet may prolong QT and cause electrolyte abnormalities, so bradycardia could increase the risk of torsades de pointes. Labeling advises against starting ozanimod in patients taking QT-prolonging drugs with arrhythmic potential without cardiology advice.
How serious is the interaction between Foscarnet and Ozanimod?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain an ECG before starting ozanimod and seek cardiology advice if foscarnet is ongoing. Monitor heart rate, QTc and electrolytes.
What other medicines interact with Foscarnet?
MediHelp also lists interactions of Foscarnet with, for example, Cidofovir, Pimozide, Thioridazine. The full list is on the Foscarnet page.
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