Drug interactions
Foscarnet + Sevoflurane
Severity: Moderate
Foscarnet and Sevoflurane: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Sevoflurane prolongs the QT interval and foscarnet may add to this effect and lower electrolytes. Perioperative ventricular arrhythmia risk may be increased.
What this interaction means in plain words
Foscarnet and Sevoflurane can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Foscarnet belongs to Anti Virals; Sevoflurane belongs to Central Nervous System.
Why it happens
Additive QT prolongation aggravated by foscarnet-related electrolyte disturbances.
What to do
Correct potassium, magnesium and calcium before anesthesia and monitor ECG continuously during surgery.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Foscarnet
- Cidofovir + Foscarnet Contraindicated
- Foscarnet + Pimozide Contraindicated
- Foscarnet + Thioridazine Contraindicated
- Foscarnet + Vandetanib Contraindicated
- Adagrasib + Foscarnet Major
- Adefovir + Foscarnet Major
Other interactions of Sevoflurane
Frequently asked questions
Can I take Foscarnet with Sevoflurane?
MediHelp rates the interaction as moderate. Foscarnet and Sevoflurane can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Sevoflurane prolongs the QT interval and foscarnet may add to this effect and lower electrolytes. Perioperative ventricular arrhythmia risk may be increased.
How serious is the interaction between Foscarnet and Sevoflurane?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Correct potassium, magnesium and calcium before anesthesia and monitor ECG continuously during surgery.
What other medicines interact with Foscarnet?
MediHelp also lists interactions of Foscarnet with, for example, Cidofovir, Pimozide, Thioridazine. The full list is on the Foscarnet page.
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