Drug interactions
Fostemsavir + Haloperidol
Severity: Moderate
Fostemsavir and Haloperidol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Haloperidol prolongs the QT interval and can cause torsades de pointes. Fostemsavir has been associated with QT prolongation at supratherapeutic doses, so the combination may add to arrhythmia risk, mainly in patients with other risk factors.
What this interaction means in plain words
Fostemsavir and Haloperidol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Fostemsavir belongs to Anti Virals; Haloperidol belongs to Central Nervous System.
Why it happens
Additive QT prolongation through cardiac repolarization effects, with fostemsavir effect seen at supratherapeutic exposure.
What to do
Obtain a baseline ECG and correct hypokalemia and hypomagnesemia. Repeat the ECG if other QT-prolonging drugs or exposure-raising factors are present, and avoid exceeding the recommended fostemsavir dose.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Haloperidol
- Dofetilide + Haloperidol Contraindicated
- Dronedarone + Haloperidol Contraindicated
- Haloperidol + Ibutilide Contraindicated
- Haloperidol + Levoketoconazole Contraindicated
- Haloperidol + Panobinostat Contraindicated
- Haloperidol + Pimozide Contraindicated
Other interactions of Fostemsavir
- Apalutamide + Fostemsavir Contraindicated
- Carbamazepine + Fostemsavir Contraindicated
- Enzalutamide + Fostemsavir Contraindicated
- Fostemsavir + Mitotane Contraindicated
- Fostemsavir + Phenytoin Contraindicated
- Fostemsavir + Rifampicin Contraindicated
Frequently asked questions
Can I take Fostemsavir with Haloperidol?
MediHelp rates the interaction as moderate. Fostemsavir and Haloperidol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Haloperidol prolongs the QT interval and can cause torsades de pointes. Fostemsavir has been associated with QT prolongation at supratherapeutic doses, so the combination may add to arrhythmia risk, mainly in patients with other risk factors.
How serious is the interaction between Fostemsavir and Haloperidol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain a baseline ECG and correct hypokalemia and hypomagnesemia. Repeat the ECG if other QT-prolonging drugs or exposure-raising factors are present, and avoid exceeding the recommended fostemsavir dose.
What other medicines interact with Haloperidol?
MediHelp also lists interactions of Haloperidol with, for example, Dofetilide, Dronedarone, Ibutilide. The full list is on the Haloperidol page.
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