Drug interactions
Furosemide + Treprostinil
Severity: Minor
Furosemide and Treprostinil: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Treprostinil is a vasodilator that lowers blood pressure, and furosemide reduces blood pressure through volume depletion. Together they may produce additive hypotension, especially at treprostinil initiation or dose increases.
What this interaction means in plain words
Furosemide and Treprostinil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Furosemide belongs to Cardiovascular; Treprostinil belongs to Cardiovascular.
Why it happens
Additive blood pressure lowering from vasodilation and diuretic-induced volume reduction.
What to do
Monitor blood pressure and volume status when starting or titrating treprostinil in patients on furosemide, and reduce the diuretic dose if symptomatic hypotension occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Furosemide
- Amifostine + Furosemide Major
- Amikacin + Furosemide Major
- Carbenoxolone + Furosemide Major
- Cephaloridine + Furosemide Major
- Cisplatin + Furosemide Major
- Digoxin + Furosemide Major
Other interactions of Treprostinil
Frequently asked questions
Can I take Furosemide with Treprostinil?
MediHelp rates the interaction as minor. Furosemide and Treprostinil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Treprostinil is a vasodilator that lowers blood pressure, and furosemide reduces blood pressure through volume depletion. Together they may produce additive hypotension, especially at treprostinil initiation or dose increases.
How serious is the interaction between Furosemide and Treprostinil?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and volume status when starting or titrating treprostinil in patients on furosemide, and reduce the diuretic dose if symptomatic hypotension occurs.
What other medicines interact with Furosemide?
MediHelp also lists interactions of Furosemide with, for example, Amifostine, Amikacin, Carbenoxolone. The full list is on the Furosemide page.
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