Drug interactions
Galantamine + Nevirapine
Severity: Minor
Galantamine and Nevirapine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Nevirapine may modestly reduce galantamine levels, which could reduce its benefit. Galantamine is cleared by both CYP2D6 and CYP3A4, so the effect is expected to be small.
What this interaction means in plain words
Galantamine and Nevirapine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Galantamine belongs to Central Nervous System; Nevirapine belongs to Anti Virals.
Why it happens
Nevirapine induces CYP3A4, increasing galantamine metabolism.
What to do
No routine dose change is needed. Monitor cognitive response and adjust if benefit diminishes.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Nevirapine
- Elbasvir / grazoprevir + Nevirapine Contraindicated
- Nevirapine + Ranolazine Contraindicated
- Nevirapine + St john's wort Contraindicated
- Abemaciclib + Nevirapine Major
- Acalabrutinib + Nevirapine Major
- Amobarbital + Nevirapine Major
Other interactions of Galantamine
- Galantamine + Memantine-donepezil Major
- Galantamine + Physostigmine Major
- Galantamine + Ponesimod Major
- Galantamine + Rivastigmine Major
- Amifampridine + Galantamine Moderate
- Amiodarone + Galantamine Moderate
Frequently asked questions
Can I take Galantamine with Nevirapine?
MediHelp rates the interaction as minor. Galantamine and Nevirapine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Nevirapine may modestly reduce galantamine levels, which could reduce its benefit. Galantamine is cleared by both CYP2D6 and CYP3A4, so the effect is expected to be small.
How serious is the interaction between Galantamine and Nevirapine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine dose change is needed. Monitor cognitive response and adjust if benefit diminishes.
What other medicines interact with Nevirapine?
MediHelp also lists interactions of Nevirapine with, for example, Elbasvir / grazoprevir, Ranolazine, St john's wort. The full list is on the Nevirapine page.
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