Drug reference
nevirapine
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Anti Virals (Antiretroviral)
Mechanism of action
Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI); activity against HIV-1 by binding to reverse transcriptase, and thereby blocking RNA- and DNA-dependent DNA polymerase actions including HIV-1 replication Does not require intracellular phosphorylation for activity
Common side effects
- Rash
- Neutropenia
- Headache
- Fever
- Diarrhea
Contraindications
- Hypersensitivity Moderate or severe hepatic impairment (Child-Pugh class B or C) Coadministration with drugs (eg, CYP inducers) where significant decreases in nevirapine plasma concentrations may occur, which may result in loss of virologic response and possible resistance and cross-resistanc…
Known interactions (7)
- carbamazepine + nevirapine Major
- efavirenz + nevirapine Major
- cariprazine + nevirapine Moderate
- dronedarone + nevirapine Moderate
- ergotamine + nevirapine Moderate
- erythromycin + nevirapine Moderate
- everolimus + nevirapine Moderate
Related conditions
Frequently asked questions
What drug class is nevirapine?
nevirapine belongs to: Anti Virals.
How does nevirapine work?
Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI); activity against HIV-1 by binding to reverse transcriptase, and thereby blocking RNA- and DNA-dependent DNA polymerase actions including HIV-1 replication Does not require intracellular phosphorylation for activity
What are the common side effects of nevirapine?
Rash, Neutropenia, Headache, Fever, Diarrhea
Which drugs interact with nevirapine?
carbamazepine, efavirenz, cariprazine, dronedarone, ergotamine, erythromycin, everolimus
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