Drug interactions
Gemfibrozil + Insulin degludec-liraglutide
Severity: Minor
Gemfibrozil and Insulin degludec-liraglutide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Gemfibrozil may modestly lower glucose and could add to the effect of insulin and liraglutide. Clinically significant hypoglycemia is uncommon.
What this interaction means in plain words
Gemfibrozil and Insulin degludec-liraglutide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Gemfibrozil belongs to Cardiovascular; Insulin degludec-liraglutide belongs to Endocrine.
Why it happens
Possible additive glucose lowering through improved insulin sensitivity.
What to do
Monitor glucose when gemfibrozil is started or stopped. Reduce the insulin dose if hypoglycemia occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Insulin degludec-liraglutide
Other interactions of Gemfibrozil
- Daprodustat + Gemfibrozil Contraindicated
- Elagolix + Gemfibrozil Contraindicated
- Gemfibrozil + Mavacamten Contraindicated
- Gemfibrozil + Metformin-repaglinide Contraindicated
- Gemfibrozil + Ombitasvir / paritaprevir / ritonavir and dasabuvir Contraindicated
- Gemfibrozil + Repaglinide Contraindicated
Frequently asked questions
Can I take Gemfibrozil with Insulin degludec-liraglutide?
MediHelp rates the interaction as minor. Gemfibrozil and Insulin degludec-liraglutide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Gemfibrozil may modestly lower glucose and could add to the effect of insulin and liraglutide. Clinically significant hypoglycemia is uncommon.
How serious is the interaction between Gemfibrozil and Insulin degludec-liraglutide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor glucose when gemfibrozil is started or stopped. Reduce the insulin dose if hypoglycemia occurs.
What other medicines interact with Insulin degludec-liraglutide?
MediHelp also lists interactions of Insulin degludec-liraglutide with, for example, Albiglutide, Chlorpropamide, Clozapine. The full list is on the Insulin degludec-liraglutide page.
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