Drug interactions
Gemifloxacin + Magnesium
Severity: Moderate
Gemifloxacin and Magnesium: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Magnesium-containing products can reduce oral gemifloxacin absorption, risking subtherapeutic antibiotic exposure.
What this interaction means in plain words
Gemifloxacin and Magnesium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Gemifloxacin belongs to Anti Bacterial; Magnesium belongs to Gastrointestinal Tract.
Why it happens
Magnesium cations chelate gemifloxacin in the gut, forming poorly absorbed complexes.
What to do
Give gemifloxacin at least 2 hours before or 3 hours after magnesium-containing products.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Magnesium
- Ciprofloxacin + Magnesium Major
- Magnesium + Pancuronium Major
- Magnesium + Rocuronium Major
- Magnesium + Vecuronium Major
- Amikacin + Magnesium Moderate
- Amphotericin b deoxycholate + Magnesium Moderate
Other interactions of Gemifloxacin
- Arsenic trioxide + Gemifloxacin Contraindicated
- Dofetilide + Gemifloxacin Contraindicated
- Gemifloxacin + Ibutilide Contraindicated
- Gemifloxacin + Pimozide Contraindicated
- Gemifloxacin + Thioridazine Contraindicated
- Gemifloxacin + Vandetanib Contraindicated
Frequently asked questions
Can I take Gemifloxacin with Magnesium?
MediHelp rates the interaction as moderate. Gemifloxacin and Magnesium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Magnesium-containing products can reduce oral gemifloxacin absorption, risking subtherapeutic antibiotic exposure.
How serious is the interaction between Gemifloxacin and Magnesium?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give gemifloxacin at least 2 hours before or 3 hours after magnesium-containing products.
What other medicines interact with Magnesium?
MediHelp also lists interactions of Magnesium with, for example, Ciprofloxacin, Pancuronium, Rocuronium. The full list is on the Magnesium page.
Full monographs, dosing and an interaction checker in the MediHelp app
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