Drug interactions
Gentamicin + Ipratropium-salbutamol
Severity: Minor
Gentamicin and Ipratropium-salbutamol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Gentamicin can cause renal potassium and magnesium wasting, and salbutamol shifts potassium into cells. Together they may lead to hypokalemia that is more pronounced in patients receiving high-dose or nebulized salbutamol. Hypokalemia can promote arrhythmias and muscle weakness.
What this interaction means in plain words
Gentamicin and Ipratropium-salbutamol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Gentamicin belongs to Anti Bacterial; Ipratropium-salbutamol belongs to Respiratory.
Why it happens
Additive lowering of serum potassium through aminoglycoside renal tubular wasting and beta-2 mediated cellular uptake.
What to do
Monitor potassium and magnesium during gentamicin therapy, especially with frequent salbutamol use, and replace deficits as needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ipratropium-salbutamol
Other interactions of Gentamicin
- Cidofovir + Gentamicin Contraindicated
- Adefovir + Gentamicin Major
- Amikacin + Gentamicin Major
- Amlodipine-hydrochlorothiazide-valsartan + Gentamicin Major
- Amphotericin b deoxycholate + Gentamicin Major
- Amphotericin b + Gentamicin Major
Frequently asked questions
Can I take Gentamicin with Ipratropium-salbutamol?
MediHelp rates the interaction as minor. Gentamicin and Ipratropium-salbutamol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Gentamicin can cause renal potassium and magnesium wasting, and salbutamol shifts potassium into cells. Together they may lead to hypokalemia that is more pronounced in patients receiving high-dose or nebulized salbutamol. Hypokalemia can promote arrhythmias and muscle weakness.
How serious is the interaction between Gentamicin and Ipratropium-salbutamol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor potassium and magnesium during gentamicin therapy, especially with frequent salbutamol use, and replace deficits as needed.
What other medicines interact with Ipratropium-salbutamol?
MediHelp also lists interactions of Ipratropium-salbutamol with, for example, Amisulpride, Arsenic trioxide, Carvedilol. The full list is on the Ipratropium-salbutamol page.
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